Traditional education. which is mainly based on evaluating theoretical content at the end of a course. is not in keeping with the skillset we require in the twenty-first century. Today. we need creative and innovative individuals who can think critically. who are capable of learning to learn. and who have complex problem-solving skills. We need people who can work collaboratively using transdisciplinary communication skills. We need citizens who are aware of local needs but have a global vision. They must make decisions not only based on their own well-being. but also in the best interests of the community and the planet. They must understand that the solution requires a balance. People can acquire these skills through design thinking. which builds the learning process by carrying out projects. and theorizes based on set challenges. Biodesign for High Schools is a pedagogical proposal that combines scientific topics with a creative approach; it offers a plethora of possibilities to prepare future high school graduates to respond to the needs of todayâs world.